Aesthetics research
The research section of the website contains aesthetics-related research carried out by specialists around the world, including Dr Leonie Schelke, Dr Peter Velthuis, Dr Tom Decates, Dr Jonathan Kadouch & Dr Tom van Eijk.
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The information is updated automatically on a daily basis.
Abstracts & full-text articles are provided, where available.
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Recent articles include:
Jani van Loghem
PMID: 39480041
Dermatol Surg. 2024 Nov 1;50(11S):S172-S176. doi: 10.1097/DSS.0000000000004437. Epub 2024 Oct 10.
ABSTRACT
BACKGROUND: A growing population of patients is seeking treatments that not only affect their overlying features but also restore a more biologically youthful structure and function to the underlying tissue. These strategies are part of what is known as regenerative aesthetics (RA). As an emergent field, clarity regarding the precise definitions and aims of RA and methods to measure the regenerative capacity of RA treatments are lacking.
METHODS: A panel of 6 multidisciplinary experts discussed the foundational aspects of RA. Consensus statements covered aspects of RA including terminology, goals of treatment, treatment strategies, and biological benchmarks indicating regeneration. Consensus on a statement was defined as ≥75% agreement.
RESULTS: Panelists emphasized the importance of natural, youthful tissue architecture and function including cellular and extracellular components. Replacement of a single biological component was not considered sufficient for an aesthetic treatment to be described as regenerative. Rather, the relative amounts, ratios, types, and organization are important to determine regenerative potential. Calcium hydroxylapatite is an example of an aesthetic injectable with evidence of regenerative capacity, as demonstrated by its ability to improve collagen type I/III ratios as well as induce the production of elastin and proteoglycans, which ultimately improve measures of skin quality.
Jani van Loghem
PMID: 39460517
J Cosmet Dermatol. 2024 Oct 26. doi: 10.1111/jocd.16649. Online ahead of print.
NO ABSTRACT
Ximena Wortsman
PMID: 39409920
Cancers (Basel). 2024 Sep 27;16(19):3301. doi: 10.3390/cancers16193301.
ABSTRACT
BACKGROUND: Skin cancer is the most common cancer in human beings. Ultrasound is a powerful and non-invasive imaging technique that has expanded its use in dermatology, including in the skin cancer field. The full range of critical anatomical information provided by ultrasound cannot be deduced from a naked eye examination, palpation, or other imaging techniques such as dermoscopy, confocal microscopy, magnetic resonance imaging, or PET-CT (Positron Emission Tomography-Computed Tomography).
METHODS: This review practically analyzes the main ultrasonographic features of the most common types of skin cancers and the performance of the locoregional staging according to the literature, which is illustrated by state-of-the-art clinical and ultrasonographic correlations.
RESULTS: The most common types of skin cancer show recognizable ultrasonographic patterns.
CONCLUSIONS: Among the current radiological imaging techniques, ultrasound has the highest axial spatial resolution. Compared to other imaging techniques used in dermatology, it shows the great advantage of penetrating the soft tissues thoroughly, which allows us to detect and identify the most common skin types of skin cancer, including both the primary tumor and its locoregional metastases.